Platelets as cellular effectors of inflammation in vascular diseases
MT Rondina, AS Weyrich, GA Zimmerman - Circulation research, 2013 - Am Heart Assoc
MT Rondina, AS Weyrich, GA Zimmerman
Circulation research, 2013•Am Heart AssocPlatelets are chief effector cells in hemostasis. In addition, they are multifaceted
inflammatory cells with functions that span the continuum from innate immune responses to
adaptive immunity. Activated platelets have key thromboinflammatory activities in a variety of
vascular disorders and vasculopathies. Recently identified inflammatory and immune
activities provide insights into the biology of these versatile blood cells that are directly
relevant to human vascular diseases.
inflammatory cells with functions that span the continuum from innate immune responses to
adaptive immunity. Activated platelets have key thromboinflammatory activities in a variety of
vascular disorders and vasculopathies. Recently identified inflammatory and immune
activities provide insights into the biology of these versatile blood cells that are directly
relevant to human vascular diseases.
Platelets are chief effector cells in hemostasis. In addition, they are multifaceted inflammatory cells with functions that span the continuum from innate immune responses to adaptive immunity. Activated platelets have key thromboinflammatory activities in a variety of vascular disorders and vasculopathies. Recently identified inflammatory and immune activities provide insights into the biology of these versatile blood cells that are directly relevant to human vascular diseases.
Am Heart Assoc