Cardiotoxin 1 from cobra (Naja naja atra) venom causes necrosis of skeletal muscle in vivo

CL Ownby, JE Fletcher, TR Colberg - Toxicon, 1993 - Elsevier
Abstract CL Ownby, JE Fletcher and TR Colberg. Cardiotoxin 1 from cobra (Naja naja atra)
venom causes necrosis of skeletal muscle in vivo. Toxicon31, 697–709, 1993.—Cardiotoxin
1 from cobra (Naja naja atra) venom was tested for its ability to cause necrosis of skeletal
muscle cells after im injection into mice. Light and electron microscopic examination of
tissue indicated that the toxin caused necrosis of skeletal muscle as early as 30 min after
injection. The plasma membranes of affected cells were ruptured in the area of delta lesions …