dlk1/FA1 (delta-like 1/fetal antigen-1) is a member of the epidermal growth factor-like
homeotic protein family whose expression is known to modulate the differentiation signals of
mesenchymal and hematopoietic stem cells in bone marrow. We have demonstrated
previously that Dlk1 can maintain the human bone marrow mesenchymal stem cells (hMSC)
in an undifferentiated state. To identify the molecular mechanisms underlying these effects,
we compared the basal gene expression pattern in Dlk1-overexpressing hMSC cells (hMSC …