Role of dopamine in the physiology of T-cells and dendritic cells

R Pacheco, CE Prado, MJ Barrientos… - Journal of …, 2009 - Elsevier
Dendritic cells (DCs) are responsible for priming T-cells and for promoting their
differentiation from naïve T-cells into appropriate effector cells. Because of their fundamental
roles in controlling immunity, DCs and T-cells require tight regulatory mechanisms. Several
studies have shown that dopamine, not only mediate interactions into the nervous system,
but can also contribute to the modulation of immunity. Here, we review the emerging role of
this neurotransmitter as a regulator of DC and T-cell physiology and, in turn, immune …