Neurons and glia in spinal sensory ganglia derive from multipotent neural crest-derived
stem cells. In contrast to neural progenitor cells in the central nervous system, neural crest
progenitors coexist with differentiated sensory neurons all throughout the neurogenic period.
Thus, developing sensory ganglia are advantageous for determining the possible influence
of cell-cell interactions in the regulation of precursor proliferation and neurogenesis.
Neurotrophins are important regulators of neuronal survival in the developing vertebrate …