Experimental acute pancreatitis—a quantification of dynamics at enzymic and histomorphologic levels
H Spormann, A Sokolowski, G Letko - Pathology-Research and Practice, 1989 - Elsevier
To study the dynamics of pathomorphologic alterations in the development of acute
epancreatitis (AP) and the corresponding changes of the patterns of pancreatic enzymes in
rats AP was induced by: 1) combination of a pancreatic juice edema and temporary
pancreatic ischemia, ii) by intraductal instillation of trypsin, and iii) by trypsin instillation in
combination with ischemia. At 4, 8 and 24 h postoperatively the histologic findings and the
activities oflipase and α-amylase in the pancreas and the serum were analyzed. The …
epancreatitis (AP) and the corresponding changes of the patterns of pancreatic enzymes in
rats AP was induced by: 1) combination of a pancreatic juice edema and temporary
pancreatic ischemia, ii) by intraductal instillation of trypsin, and iii) by trypsin instillation in
combination with ischemia. At 4, 8 and 24 h postoperatively the histologic findings and the
activities oflipase and α-amylase in the pancreas and the serum were analyzed. The …