DNA methylation levels in normal and chemically-transformed mouse 3T3 cells
ES Diala, RM Hoffman - Biochemical and Biophysical Research …, 1982 - Elsevier
ES Diala, RM Hoffman
Biochemical and Biophysical Research Communications, 1982•ElsevierNormal mouse embryo 3T3 cell cultures and those oncogenically transformed by the
chemical carcinogens benzo (a) pyrene and methylcholanthrene were analyzed by high
performance liquid chromatography to determine the 5-methylcytosine to cytosine base
ratios in their total genomic DNA. The DNA methylation levels appear to be approximately
equal in the three cell lines examined.
chemical carcinogens benzo (a) pyrene and methylcholanthrene were analyzed by high
performance liquid chromatography to determine the 5-methylcytosine to cytosine base
ratios in their total genomic DNA. The DNA methylation levels appear to be approximately
equal in the three cell lines examined.
Abstract
Normal mouse embryo 3T3 cell cultures and those oncogenically transformed by the chemical carcinogens benzo(a)pyrene and methylcholanthrene were analyzed by high performance liquid chromatography to determine the 5-methylcytosine to cytosine base ratios in their total genomic DNA. The DNA methylation levels appear to be approximately equal in the three cell lines examined.
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