Drugs that block mechanically-evoked pain would be useful for many common pain
conditions, but appropriate drug development targets have yet to be defined. There is
increasing evidence that both peripheral sensory neuron wiring patterns as well as the
expression of transducing molecules are important for modality specific pain sensations.
Progress in identifying the cell types, candidate transducing molecules and wiring patterns
involved in mechanosensation has been dramatic over the past few years. Here we focus on …