Separation of retinoblastoma and esterase D loci in a patient with sporadic retinoblastoma and del (13)(q14. 1q22. 3)

RS Sparkes, MC Sparkes, RE Kalina, RA Pagon… - Human genetics, 1984 - Springer
RS Sparkes, MC Sparkes, RE Kalina, RA Pagon, DJ Salk, CM Disteche
Human genetics, 1984Springer
A chromosome 13 deletion in a patient with sporadic retinoblastoma appears to have
separated the loci for retinoblastoma and esterase D. This study indicates that:(1) the
retinoblastoma locus is distinct from the esterase D locus; and (2) the linear order of these
genes is centromere-esterase D-retinoblastoma.
Summary
A chromosome 13 deletion in a patient with sporadic retinoblastoma appears to have separated the loci for retinoblastoma and esterase D. This study indicates that: (1) the retinoblastoma locus is distinct from the esterase D locus; and (2) the linear order of these genes is centromere-esterase D-retinoblastoma.
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