An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms

RH Hruban, K Takaori, DS Klimstra… - The American journal …, 2004 - journals.lww.com
Invasive pancreatic ductal adenocarcinoma is an almost uniformly fatal disease. Several
distinct noninvasive precursor lesions can give rise to invasive adenocarcinoma of the
pancreas, and the prevention, detection, and treatment of these noninvasive lesions offers
the potential to cure early pancreatic cancers. Noninvasive precursors of invasive ductal
adenocarcinoma of the pancreas include pancreatic intraepithelial neoplasias (PanINs),
intraductal papillary mucinous neoplasms (IPMNs), and mucinous cystic neoplasms …