[HTML][HTML] Extension of chronological lifespan by hexokinase mutation in Kluyveromyces lactis involves increased level of the mitochondrial chaperonin Hsp60

L Rizzetto, E Zanni, D Uccelletti, I Ferrero… - Journal of Aging …, 2012 - hindawi.com
Oxidative damage, mitochondrial dysfunction, genomic instability, and telomere shortening
represent all molecular processes proposed as causal factors in aging. Lifespan can be
increased by metabolism through an influence on such processes. Glucose reduction
extends chronological lifespan (CLS) of Saccharomyces cerevisiae through metabolic
adaptation to respiration. To answer the question if the reduced CLS could be ascribed to
glucose per se or to glucose repression of respiratory enzymes, we used the Kluyveromyces …

[PDF][PDF] Research Article Extension of Chronological Lifespan by Hexokinase Mutation in Kluyveromyces lactis Involves Increased Level of the Mitochondrial …

L Rizzetto, E Zanni, D Uccelletti, I Ferrero, P Goffrini - 2012 - academia.edu
Oxidative damage, mitochondrial dysfunction, genomic instability, and telomere shortening
represent all molecular processes proposed as causal factors in aging. Lifespan can be
increased by metabolism through an influence on such processes. Glucose reduction
extends chronological lifespan (CLS) of Saccharomyces cerevisiae through metabolic
adaptation to respiration. To answer the question if the reduced CLS could be ascribed to
glucose per se or to glucose repression of respiratory enzymes, we used the Kluyveromyces …