Interferon-gamma-induced expressions of heat shock protein 60 and heat shock protein 10 in C6 astroglioma cells: identification of the signal transducers and …

SW Kim, JB Kim, JH Kim, JK Lee - Neuroreport, 2007 - journals.lww.com
Heat shock protein 60 and heat shock protein 10 are mitochondrial chaperonin proteins.
Here, we report that the expressions of heat shock protein 60 and heat shock protein 10
were upregulated in interferon-γ-treated C6 astroglioma cells, and the 582 bp in the
bidirectional promoter of the heat shock protein 60 and heat shock protein 10 genes is
responsible for interferon-γ-induced induction. The induction of heat shock protein 60 and
heat shock protein 10 by interferon-γ was virtually abolished by introducing mutations into …