[HTML][HTML] Mycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunity

Y Singh, V Kaul, A Mehra, S Chatterjee, S Tousif… - Journal of Biological …, 2013 - ASBMB
Mycobacterium tuberculosis resides and replicates within host phagocytes by modulating
host microbicidal responses. In addition, it suppresses the production of host protective
cytokines to prevent activation of and antigen presentation by M. tuberculosis-infected cells,
causing dysregulation of host protective adaptive immune responses. Many cytokines are
regulated by microRNAs (miRNAs), a newly discovered class of small noncoding RNAs,
which have been implicated in modulating host immune responses in many bacterial and …