Practical considerations in the development and refinement of subcallosal cingulate white matter deep brain stimulation for treatment-resistant depression
P Riva-Posse, PE Holtzheimer, SJ Garlow… - World Neurosurgery, 2013 - Elsevier
P Riva-Posse, PE Holtzheimer, SJ Garlow, HS Mayberg
World Neurosurgery, 2013•ElsevierBackground Deep brain stimulation has been investigated in the past decade as a viable
intervention for treatment-resistant depression. Methods Several anatomic targets have
been tested, with the most extensive published experience found for the subcallosal
cingulate (SCC) white matter. Results This article reviews the current state of clinical
research of SCC deep brain stimulation for treatment-resistant depression, including an
overview of the rationale for targeting SCC, practical considerations for subject recruitment …
intervention for treatment-resistant depression. Methods Several anatomic targets have
been tested, with the most extensive published experience found for the subcallosal
cingulate (SCC) white matter. Results This article reviews the current state of clinical
research of SCC deep brain stimulation for treatment-resistant depression, including an
overview of the rationale for targeting SCC, practical considerations for subject recruitment …
Background
Deep brain stimulation has been investigated in the past decade as a viable intervention for treatment-resistant depression.
Methods
Several anatomic targets have been tested, with the most extensive published experience found for the subcallosal cingulate (SCC) white matter.
Results
This article reviews the current state of clinical research of SCC deep brain stimulation for treatment-resistant depression, including an overview of the rationale for targeting SCC, practical considerations for subject recruitment and evaluation, surgical planning, and stimulation parameters.
Conclusion
Clinical management of patients in the initial and long-term naturalistic phases of treatment, including the potential role for psychotherapeutic rehabilitation, is discussed.
Elsevier