Bilateral deep brain stimulation of the globus pallidus to treat tardive dyskinesia
P Damier, S Thobois, T Witjas, E Cuny… - Archives of general …, 2007 - jamanetwork.com
Context Tardive dyskinesia (TD) is a common and potentially disabling disorder induced by
use of antipsychotic drugs for which medical treatment often gives disappointing results.
Objective To assess the efficacy of bilateral deep brain stimulation of the internal part of the
globus pallidus to treat severe TD. Design Prospective phase 2 multicenter study. Setting Six
French university hospitals. Patients Patients with severe TD refractory to medical treatment
were studied to evaluate the severity of abnormal involuntary movements before and after 6 …
use of antipsychotic drugs for which medical treatment often gives disappointing results.
Objective To assess the efficacy of bilateral deep brain stimulation of the internal part of the
globus pallidus to treat severe TD. Design Prospective phase 2 multicenter study. Setting Six
French university hospitals. Patients Patients with severe TD refractory to medical treatment
were studied to evaluate the severity of abnormal involuntary movements before and after 6 …