Context Obsessive-compulsive disorder (OCD) is a chronic psychiatric disorder that affects
2% of the general population. Even when the best available treatments are applied,
approximately 10% of patients remain severely afflicted and run a long-term deteriorating
course of OCD. Objective To determine whether bilateral deep brain stimulation of the
nucleus accumbens is an effective and safe treatment for treatment-refractory OCD. Design
The study consisted of an open 8-month treatment phase, followed by a double-blind …