Long-term results of the MD Anderson randomized dose-escalation trial for prostate cancer
DA Kuban, SL Tucker, L Dong, G Starkschall… - International Journal of …, 2008 - Elsevier
PURPOSE: To report the long-term results of a randomized radiotherapy dose escalation
trial for prostate cancer. METHODS AND MATERIALS: From 1993 to 1998, a total of 301
patients with stage T1b to T3 prostate cancer were accrued to a randomized external beam
dose escalation trial using 70 Gy versus 78 Gy. The median follow-up is now 8.7 years.
Kaplan-Meier analysis was used to compute rates of prostate-specific antigen (PSA) failure
(nadir+ 2), clinical failure, distant metastasis, disease-specific, and overall survival as well as …
trial for prostate cancer. METHODS AND MATERIALS: From 1993 to 1998, a total of 301
patients with stage T1b to T3 prostate cancer were accrued to a randomized external beam
dose escalation trial using 70 Gy versus 78 Gy. The median follow-up is now 8.7 years.
Kaplan-Meier analysis was used to compute rates of prostate-specific antigen (PSA) failure
(nadir+ 2), clinical failure, distant metastasis, disease-specific, and overall survival as well as …