Impact of chemokine receptor CX3CR1 in human renal allograft rejection
U Hoffmann, T Bergler, S Segerer, P Rümmele… - Transplant …, 2010 - Elsevier
Chemokine receptors play pivotal roles for leukocyte recruitment in acute and chronic
inflammatory processes. This study was performed to analyze the expression, distribution
and cellular localization of CX3CR1 in human renal transplant biopsies and to assess its
role as potential diagnostic and prognostic marker. CX3CR1 was prospectively analyzed in
174 renal graft biopsies from patients with normal morphology (n= 76), antibody-mediated
acute rejection (n= 6), acute tubulointerstitial rejection (n= 27), acute vascular rejection (n …
inflammatory processes. This study was performed to analyze the expression, distribution
and cellular localization of CX3CR1 in human renal transplant biopsies and to assess its
role as potential diagnostic and prognostic marker. CX3CR1 was prospectively analyzed in
174 renal graft biopsies from patients with normal morphology (n= 76), antibody-mediated
acute rejection (n= 6), acute tubulointerstitial rejection (n= 27), acute vascular rejection (n …