The biological role of inflammation in atherosclerosis

BW Wong, A Meredith, D Lin, BM McManus - Canadian Journal of …, 2012 - Elsevier
The concept of the involvement of inflammation in the pathogenesis of atherosclerosis has
existed since the 1800s, stemming from sentinel pathologic observations made by Rudolf
Virchow, Karl Rokitansky, and others. Our understanding of the complex role played by
immune and inflammatory mediators in the initiation and progression of atherosclerosis has
evolved considerably in the intervening years, and today, a dramatically evolved
understanding of these processes has led to advances in both diagnostic and prognostic …