Serum 7α-hydroxy-4-cholesten-3-one and selenohomocholyltaurine (SeHCAT) whole body retention in the assessment of bile acid induced diarrhoea

WG Brydon, H Nyhlin, MA Eastwood… - European journal of …, 1996 - journals.lww.com
Objective: To assess the reliability of serum 7 [alpha]-hydroxy-4-cholesten-3-one (7 [alpha]-
3ox-C) in the differential diagnosis of bile acid induced diarrhoea by comparison with
75selenohomocholyltaurine whole body retention (SeHCAT WBR). Design: One hundred
and sixty-four patients with chronic diarrhoea were investigated prospectively in two centres
(Edinburgh and Sweden) by two different tests which measure bile acid loss or synthesis:
the SeHCAT test which measures the 7-day SeHCAT WBR and serum 7 [alpha]-3ox-C …