Epigenetic side-effects of common pharmaceuticals: a potential new field in medicine and pharmacology

AB Csoka, M Szyf - Medical hypotheses, 2009 - Elsevier
The term “Epigenetics” refers to DNA and chromatin modifications that persist from one cell
division to the next, despite a lack of change in the underlying DNA sequence. The
“epigenome” refers to the overall epigenetic state of a cell, and serves as an interface
between the environment and the genome. The epigenome is dynamic and responsive to
environmental signals not only during development, but also throughout life; and it is
becoming increasingly apparent that chemicals can cause changes in gene expression that …