Duration of brain death and cold ischemia time, but not warm ischemia time, increases expression of genes associated with apoptosis in transplanted kidneys from …

P Chudoba, D Kamińska… - Transplantation …, 2011 - Elsevier
Apoptosis is one of the most important mechanisms leading to kidney graft injury during
transplantation. The aim of this study was to assess the expression of genes involved in
apoptosis in transplanted kidneys derived from deceased donors (DD) at various stages of
the transplant procedure, seventy eight transplanted kidneys procured from 43 DD were
included in this study. As a baseline control for gene expressions we used six kidney
allografts obtained from living donors (LD). Three core biopsies were performed: biopsy 1 …