Localization of the gene encoding human factor V to chromosome 1q21–25
H Wang, DC Riddell, ER Guinto, RTA MacGillivray… - Genomics, 1988 - Elsevier
H Wang, DC Riddell, ER Guinto, RTA MacGillivray, JL Hamerton
Genomics, 1988•ElsevierThe gene encoding human coagulation Factor V (FV), one of the cofactors in the blood
clotting process, has been mapped to chromosome 1 by both Southern hybridization to DNA
from human-hamster somatic cell hybrids and in situ hybridization. The whole plasmid
pUC3A containing a 1.5-kb cDNA sequence for FV was 32 P-labeled for Southern analysis
and 3 H-labeled for in situ hybridization to metaphase chromosomes. The results localized
the FV gene to the region of 1q21–25.
clotting process, has been mapped to chromosome 1 by both Southern hybridization to DNA
from human-hamster somatic cell hybrids and in situ hybridization. The whole plasmid
pUC3A containing a 1.5-kb cDNA sequence for FV was 32 P-labeled for Southern analysis
and 3 H-labeled for in situ hybridization to metaphase chromosomes. The results localized
the FV gene to the region of 1q21–25.
Abstract
The gene encoding human coagulation Factor V (FV), one of the cofactors in the blood clotting process, has been mapped to chromosome 1 by both Southern hybridization to DNA from human-hamster somatic cell hybrids and in situ hybridization. The whole plasmid pUC3A containing a 1.5-kb cDNA sequence for FV was 32P-labeled for Southern analysis and 3H-labeled for in situ hybridization to metaphase chromosomes. The results localized the FV gene to the region of 1q21–25.
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