Establishment of Hox vertebral identities in the embryonic spine precursors
T Iimura, N Denans, O Pourquié - Current topics in developmental biology, 2009 - Elsevier
The vertebrate spine exhibits two striking characteristics. The first one is the periodic
arrangement of its elements—the vertebrae—along the anteroposterior axis. This
segmented organization is the result of somitogenesis, which takes place during
organogenesis. The segmentation machinery involves a molecular oscillator—the
segmentation clock—which delivers a periodic signal controlling somite production. During
embryonic axis elongation, this signal is displaced posteriorly by a system of traveling …
arrangement of its elements—the vertebrae—along the anteroposterior axis. This
segmented organization is the result of somitogenesis, which takes place during
organogenesis. The segmentation machinery involves a molecular oscillator—the
segmentation clock—which delivers a periodic signal controlling somite production. During
embryonic axis elongation, this signal is displaced posteriorly by a system of traveling …