Selective induction of a heat shock gene in fibre tracts and cerebellar neurons of the rabbit brain detected by in situ hybridization
GK Sprang, IR Brown - Molecular Brain Research, 1987 - Elsevier
In situ hybridization reveals striking regional differences in the expression of constitutive and
inducible heat shock genes in the rabbit brain. Fibre tracts throughout the brain show a
dramatic induction of heat shock mRNA after hyperthermia, a pattern consistent with a strong
glial response to heat shock. While neurons in the cerebellum exhibit a marked induction of
heat shock mRNA, neurons of the hippocampus do not. Constitutive expression of a heat
shock gene is observed in neuronal laminae of the hippocampus and cerebellum.
inducible heat shock genes in the rabbit brain. Fibre tracts throughout the brain show a
dramatic induction of heat shock mRNA after hyperthermia, a pattern consistent with a strong
glial response to heat shock. While neurons in the cerebellum exhibit a marked induction of
heat shock mRNA, neurons of the hippocampus do not. Constitutive expression of a heat
shock gene is observed in neuronal laminae of the hippocampus and cerebellum.