Autoimmune hepatitis

CP Strassburg - Best Practice & Research Clinical Gastroenterology, 2010 - Elsevier
Autoimmune hepatitis is a chronic inflammatory disease of the liver with a dismal prognosis
when left untreated. Key for the improvement of prognosis is a timely diagnosis before
cirrhosis has developed. This is reached by the exclusion of other causes of hepatitis,
elevated immunoglobulin G, autoantibody profile and histological assessment. Treatment
achieves remission rates in 80% of individuals and consists of immunosuppression with
corticosteroids and azathioprine. A recent randomised controlled multicenter trial has added …