Peripheral CD4+ CD8+ cells are the activated T cells expressed granzyme B (GrB), Foxp3, interleukin 17 (IL-17), at higher levels in Th1/Th2 cytokines
D Xie, B Hai, X Xie, L Liu, J Ayello, X Ma, J Zhang - Cellular immunology, 2009 - Elsevier
Peripheral CD4+ CD8+ T cells have been identified as a T cell subset existing in animals
and humans. However, the characterization of CD4+ CD8+ T cells, their relationship with T
memory (TM), T effector (TE), Th1/Th2, Treg and Th-17, remain unclear. This study was to
characterize the CD4+ CD8+ T cells. The results from human subjects showed that activated
T cells were CD4+ CD8+ T cells, comprised CD4hiCD8lo, CD4hiCD8hi and CD4loCD8hi
subsets. They expressed CD62Lhi/lo, granzyme B (GrB), CD25, Foxp3, interleukin 17 (IL-17) …
and humans. However, the characterization of CD4+ CD8+ T cells, their relationship with T
memory (TM), T effector (TE), Th1/Th2, Treg and Th-17, remain unclear. This study was to
characterize the CD4+ CD8+ T cells. The results from human subjects showed that activated
T cells were CD4+ CD8+ T cells, comprised CD4hiCD8lo, CD4hiCD8hi and CD4loCD8hi
subsets. They expressed CD62Lhi/lo, granzyme B (GrB), CD25, Foxp3, interleukin 17 (IL-17) …