Clinical significance of autoantibodies to soluble liver antigen in autoimmune hepatitis
S Kanzler, C Weidemann, G Gerken, HF Löhr… - Journal of …, 1999 - Elsevier
Background/Aims: Classification of autoimmune hepatitis (AIH) into different subgroups
according to autoantibody status has been proposed: type I (ANA/SMA), type II (LKM-1) and
type III (anti-SLA). However, whether type III AIH forms a clinically distinct disease entity
remains controversial. The aim of this study was to evaluate the subclassification of AIH into
ANA/SMA and anti-SLA positive patients with regard to clinical, biochemical and histologic
differences. Methods: Ninety-seven consecutive patients with a well-documented long-term …
according to autoantibody status has been proposed: type I (ANA/SMA), type II (LKM-1) and
type III (anti-SLA). However, whether type III AIH forms a clinically distinct disease entity
remains controversial. The aim of this study was to evaluate the subclassification of AIH into
ANA/SMA and anti-SLA positive patients with regard to clinical, biochemical and histologic
differences. Methods: Ninety-seven consecutive patients with a well-documented long-term …