Antibody to liver cytosol (anti-LC1) in patients with autoimmune chronic active hepatitis type 2
E Martini, N Abuaf, F Cavalli, VÉR Durand… - Hepatology, 1988 - journals.lww.com
A new autoantibody was detected by immunoprecipitation in the serum of 21 patients with
chronic active hepatitis. The antibody reacted against a soluble cytosolic antigen in liver.
The antibody was organ specific but not species specific and was therefore called antiliver
cytosol antibody Type 1 (anti-LC1). In seven of 21 cases, no other autoantibody was found;
the remaining 14 cases had anti-liver/kidney microsome antibody Type 1 (anti-LKM1). With
indirect immunofluorescence, a distinctive staining pattern was observed with the seven …
chronic active hepatitis. The antibody reacted against a soluble cytosolic antigen in liver.
The antibody was organ specific but not species specific and was therefore called antiliver
cytosol antibody Type 1 (anti-LC1). In seven of 21 cases, no other autoantibody was found;
the remaining 14 cases had anti-liver/kidney microsome antibody Type 1 (anti-LKM1). With
indirect immunofluorescence, a distinctive staining pattern was observed with the seven …