[HTML][HTML] Long-term outcomes of extended proximal gastrectomy for oesophagogastric junctional tumours

O Khan, S Goh, B Byrne, S Somers, S Mercer… - World journal of …, 2011 - Springer
O Khan, S Goh, B Byrne, S Somers, S Mercer, S Toh
World journal of surgery, 2011Springer
Background There is no consensus on the optimum approach for resection of
oesophagogastric junctional (OGJ) tumours. We prospectively evaluated the efficacy of
transabdominal radical extended proximal gastrectomy with oesophagogastric anastomosis
(EPGOG) for selected tumours of the OGJ. Methods Between 1998 and 2007, 66 selected
consecutive patients with tumours of the OGJ underwent successful EPGOG. Selection was
limited to tumours where the maximal proximal extent was 36 cm ab oral. Pre-, peri-, and …
Background
There is no consensus on the optimum approach for resection of oesophagogastric junctional (OGJ) tumours. We prospectively evaluated the efficacy of transabdominal radical extended proximal gastrectomy with oesophagogastric anastomosis (EPGOG) for selected tumours of the OGJ.
Methods
Between 1998 and 2007, 66 selected consecutive patients with tumours of the OGJ underwent successful EPGOG. Selection was limited to tumours where the maximal proximal extent was 36 cm ab oral. Pre-, peri-, and postoperative outcomes together with long-term survival data for these patients were prospectively collected.
Results
Median theatre time was 242 min (range = 120–480), with a median blood loss of 300 ml (range = 50–1720). Eighty-nine percent of patients were extubated in theatre; major complications occurred in 9 (14%) patients, with an overall in-hospital mortality rate of 8%. Thirty-five (53%) patients had nodal disease and the median lymph node yield was 13 (range = 4–36), with an R0 resection rate of 80%. In terms of long-term outcomes, the 2- and 5-year actuarial survival rates were 54 ± 6% and 41 ± 6%.
Conclusion
Extended radical proximal gastrectomy with oesophagogastric anastomosis for selected junctional tumours is a feasible technique which does not compromise oncological principles as evidenced by an excellent long-term survival rate.
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