[HTML][HTML] Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans

T Yoneshiro, S Aita, Y Kawai, T Iwanaga… - The American journal of …, 2012 - Elsevier
Background: Capsinoids—nonpungent capsaicin analogs—are known to activate brown
adipose tissue (BAT) thermogenesis and whole-body energy expenditure (EE) in small
rodents. BAT activity can be assessed by [18 F] fluorodeoxyglucose–positron emission
tomography (FDG-PET) in humans. Objectives: The aims of the current study were to
examine the acute effects of capsinoid ingestion on EE and to analyze its relation to BAT
activity in humans. Design: Eighteen healthy men aged 20–32 y underwent FDG-PET after 2 …