Effects of long-term exposure to Δ9-THC on expression of cannabinoid receptor (CB1) mRNA in different rat brain regions
S Zhuang, J Kittler, EV Grigorenko, MT Kirby… - Molecular Brain …, 1998 - Elsevier
The time course of changes across 21 days of continuous exposure to Δ9-
tetrahydrocannabinol (Δ9-THC) was assessed for the level of cannabinoid receptor (CB1)
mRNA expression in three different rat brain regions: cerebellum, hippocampus and corpus
striatum. Expression levels of CB1 mRNA were determined using semi-quantitative reverse
transcriptase–polymerase chain reaction (RT-PCR) following a protocol which included a
gene standard, 28S ribonucleic acid protein (rRNA), for normalization of levels of RNA in the …
tetrahydrocannabinol (Δ9-THC) was assessed for the level of cannabinoid receptor (CB1)
mRNA expression in three different rat brain regions: cerebellum, hippocampus and corpus
striatum. Expression levels of CB1 mRNA were determined using semi-quantitative reverse
transcriptase–polymerase chain reaction (RT-PCR) following a protocol which included a
gene standard, 28S ribonucleic acid protein (rRNA), for normalization of levels of RNA in the …