The sodium deposing function of the skin in Wistar albino rats under conditions of different salt loads were studied. 6 mEq NaCl per os was followed by an increase in sodium content of the skin on account of the exchangeable fraction. The diet with high content of sodium (15 mEq a day during 30 days) led to saturation of the skin storage structures, the blood sodium concentration after a single salt load increasing sharply. The storage of sodium in the skin is, evidently, carried out with the aid of the cation by glycosamino--glycans. The increase in exchangeable sodium of the skin under the condition of highsodium regimen is, evidently, due to an increase in sulphated GAG.