[HTML][HTML] Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase …
H Park, VK Kaushik, S Constant, M Prentki… - Journal of Biological …, 2002 - ASBMB
Changes in the concentration of malonyl-CoA in many tissues have been related to
alterations in the activity of acetyl-CoA carboxylase (ACC), the rate-limiting enzyme in its
formation. In contrast, little is known about the physiological role of malonyl-CoA
decarboxylase (MCD), an enzyme responsible for malonyl-CoA catabolism. In this study, we
examined the effects of voluntary exercise on MCD activity in rat liver, skeletal muscle, and
adipose tissue. In addition, the activity ofsn-glycerol-3-phosphate acyltransferase (GPAT) …
alterations in the activity of acetyl-CoA carboxylase (ACC), the rate-limiting enzyme in its
formation. In contrast, little is known about the physiological role of malonyl-CoA
decarboxylase (MCD), an enzyme responsible for malonyl-CoA catabolism. In this study, we
examined the effects of voluntary exercise on MCD activity in rat liver, skeletal muscle, and
adipose tissue. In addition, the activity ofsn-glycerol-3-phosphate acyltransferase (GPAT) …