[HTML][HTML] T-regulatory cell modulation: the future of cancer immunotherapy?
S Nizar, J Copier, B Meyer, M Bodman-Smith… - British journal of …, 2009 - nature.com
S Nizar, J Copier, B Meyer, M Bodman-Smith, C Galustian, D Kumar, A Dalgleish
British journal of cancer, 2009•nature.comT-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour
models. Furthermore, their activity is likely to have an effect on the effectiveness of
immunotherapeutic treatments for cancer. Here we describe the current status of developing
clinical strategies for modulating Treg activity in cancer patients.
models. Furthermore, their activity is likely to have an effect on the effectiveness of
immunotherapeutic treatments for cancer. Here we describe the current status of developing
clinical strategies for modulating Treg activity in cancer patients.
Abstract
T-regulatory cells suppress anti-tumour immunity in cancer patients and in murine tumour models. Furthermore, their activity is likely to have an effect on the effectiveness of immunotherapeutic treatments for cancer. Here we describe the current status of developing clinical strategies for modulating Treg activity in cancer patients.
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