Escherichia coli, fimbriae, bacterial persistence and host response induction in the human urinary tract
G Bergsten, B Wullt, C Svanborg - International Journal of Medical …, 2005 - Elsevier
Urinary tract infections (UTI) are among the most common bacterial infections in humans.
Symptomatic UTIs may be acute, recurrent or chronic but the most frequent form of UTI is
asymptomatic bacteruria (ABU). In ABU, the mucosa remains inert, despite the presence of
large bacterial numbers in urine. The difference in disease severity reflects the virulence of
the infecting strain and the propensity of the host to respond to infection. It is essential to
understand the molecular basis of disease diversity and the molecular interactions between …
Symptomatic UTIs may be acute, recurrent or chronic but the most frequent form of UTI is
asymptomatic bacteruria (ABU). In ABU, the mucosa remains inert, despite the presence of
large bacterial numbers in urine. The difference in disease severity reflects the virulence of
the infecting strain and the propensity of the host to respond to infection. It is essential to
understand the molecular basis of disease diversity and the molecular interactions between …