[HTML][HTML] Smoking during pregnancy influences the maternal immune response in mice and humans
JR Prins, MN Hylkema, JJHM Erwich, S Huitema… - American journal of …, 2012 - Elsevier
OBJECTIVE: During pregnancy the maternal immune system has to adapt its response to
accommodate the fetus. The objective of this study was to analyze the effects of smoking on
the maternal immune system. STUDY DESIGN: First-trimester decidual tissue and peripheral
blood of smoking and nonsmoking women were analyzed by real time reverse transcription–
polymerase chain reaction (RT-PCR) and flow cytometry. A mouse model was used to
further analyze the effects of smoking. Murine tissue was analyzed by flow cytometry, real …
accommodate the fetus. The objective of this study was to analyze the effects of smoking on
the maternal immune system. STUDY DESIGN: First-trimester decidual tissue and peripheral
blood of smoking and nonsmoking women were analyzed by real time reverse transcription–
polymerase chain reaction (RT-PCR) and flow cytometry. A mouse model was used to
further analyze the effects of smoking. Murine tissue was analyzed by flow cytometry, real …