Treatment response and relapse in antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis.
PH Nachman, SL Hogan, JC Jennette… - Journal of the American …, 1996 - journals.lww.com
In this study, the rate of remission, relapse, and treatment resistance in 107 patients with
microscopic polyangiitis and necrotizing and crescentic glomerulonephritis associated with
antineutrophil cytoplasmic autoantibodies were assessed. Patients with Wegener's
granulomatosis were excluded. Prospective criteria were identified to assess remission,
relapse, and resistant disease. Ninety-seven of the 107 patients received treatment with
corticosteroids (N= 25) or with cyclophosphamide and corticosteroids (N= 72). Of these …
microscopic polyangiitis and necrotizing and crescentic glomerulonephritis associated with
antineutrophil cytoplasmic autoantibodies were assessed. Patients with Wegener's
granulomatosis were excluded. Prospective criteria were identified to assess remission,
relapse, and resistant disease. Ninety-seven of the 107 patients received treatment with
corticosteroids (N= 25) or with cyclophosphamide and corticosteroids (N= 72). Of these …