Neuroplasticity in vagal afferent neurons involved in cough
TM Lieu, BJ Undem - Pulmonary pharmacology & therapeutics, 2011 - Elsevier
Neurotrophic factors are produced in the airways during allergic and viral inflammation.
Their selective interaction with cognate receptors on sensory nerves likely accounts for
some of the neuroplasticity that can accompany inflammatory diseases. We have previously
described a nodose Aδ fiber in the guinea pig trachea that evokes cough upon stimulation.
These nerves do not express TRPV1 and accordingly are capsaicin-insensitive. We
evaluated the neurotrophic factor expression in nodose tracheal Aδ fiber neurons using …
Their selective interaction with cognate receptors on sensory nerves likely accounts for
some of the neuroplasticity that can accompany inflammatory diseases. We have previously
described a nodose Aδ fiber in the guinea pig trachea that evokes cough upon stimulation.
These nerves do not express TRPV1 and accordingly are capsaicin-insensitive. We
evaluated the neurotrophic factor expression in nodose tracheal Aδ fiber neurons using …