FPR and FPRL1 belong to the seven-transmembrane, G protein-coupled chemoattractant
receptor superfamily. Because of their capacity to interact with bacterial chemotactic
formylated peptides, these receptors are thought to play a role in host defense against
microbial infection. Recently, a variety of novel agonists have been identified for these
receptors, including several host-derived endogenous molecules that are involved in
proinflammatory responses. Most notably is the use of FPRL1 by at least three …