[PDF][PDF] Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy

YP Yu, D Landsittel, L Jing, J Nelson, B Ren… - Journal of clinical …, 2004 - academia.edu
YP Yu, D Landsittel, L Jing, J Nelson, B Ren, L Liu, C McDonald, R Thomas, R Dhir…
Journal of clinical oncology, 2004academia.edu
Purpose The incidence of prostate cancer is frequent, occurring in almost one-third of men
older than 45 years. Only a fraction of the cases reach the stages displaying clinical
significance. Despite the advances in our understanding of prostate carcinogenesis and
disease progression, our knowledge of this disease is still fragmented. Identification of the
genes and patterns of gene expression will provide a more cohesive picture of prostate
cancer biology.
Purpose
The incidence of prostate cancer is frequent, occurring in almost one-third of men older than 45 years. Only a fraction of the cases reach the stages displaying clinical significance. Despite the advances in our understanding of prostate carcinogenesis and disease progression, our knowledge of this disease is still fragmented. Identification of the genes and patterns of gene expression will provide a more cohesive picture of prostate cancer biology.
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