Naturally occurring carbonyl compounds are mutagens Salmonella tester strain TA104
LJ Marnett, HK Hurd, MC Hollstein, DE Levin… - Mutation Research …, 1985 - Elsevier
Strains of Salmonella typhimurium that carry a nonsense mutation at the site of reversion
detect a variety of naturaly occurring and synthetic carbonyl compounds as direct-acting
mutagens. TA104 is reverted efficiently by formaldehyde, α, β-unsaturated aldehydes
(enals), and dicarbonyl compounds, such as diacetyl and glutaraldehyde. This strain is
much more sensitive to carbonyl mutagenesis than is TA100, a strain previously reported to
detect aldehydes as mutagens, or any other characterized strains of Salmonella. Long-chain …
detect a variety of naturaly occurring and synthetic carbonyl compounds as direct-acting
mutagens. TA104 is reverted efficiently by formaldehyde, α, β-unsaturated aldehydes
(enals), and dicarbonyl compounds, such as diacetyl and glutaraldehyde. This strain is
much more sensitive to carbonyl mutagenesis than is TA100, a strain previously reported to
detect aldehydes as mutagens, or any other characterized strains of Salmonella. Long-chain …