Some propose using phosphate binders in the CKD population given the association
between higher levels of phosphorus and mortality, but their safety and efficacy in this
population are not well understood. Here, we aimed to determine the effects of phosphate
binders on parameters of mineral metabolism and vascular calcification among patients with
moderate to advanced CKD. We randomly assigned 148 patients with estimated GFR= 20–
45 ml/min per 1.73 m 2 to calcium acetate, lanthanum carbonate, sevelamer carbonate, or …