[HTML][HTML] It takes KASH to hitch to the SUN

B Burke - Cell, 2012 - cell.com
Cell, 2012cell.com
LINC complexes are structures embedded within the nuclear envelope that mechanically
couple the nucleus and cytoskeleton. They consist of SUN domain proteins of the inner
nuclear membrane associated with KASH domain proteins in the outer nuclear membrane.
Atomic resolution structures of SUN-KASH pairs now provide new insight in to the
mechanisms of LINC complex assembly.
LINC complexes are structures embedded within the nuclear envelope that mechanically couple the nucleus and cytoskeleton. They consist of SUN domain proteins of the inner nuclear membrane associated with KASH domain proteins in the outer nuclear membrane. Atomic resolution structures of SUN-KASH pairs now provide new insight in to the mechanisms of LINC complex assembly.
cell.com