[HTML][HTML] Thyroid hormone and the cardiovascular system

I Klein, K Ojamaa - New England Journal of Medicine, 2001 - Mass Medical Soc
I Klein, K Ojamaa
New England Journal of Medicine, 2001Mass Medical Soc
Thyroid hormone has many effects on the heart and vascular system. 1 Many of the clinical
manifestations of hyperthyroidism are due to the ability of thyroid hormone to alter
cardiovascular hemodynamics. 2 The hemodynamic effects of hypothyroidism are opposite
to those of hyperthyroidism, although the clinical manifestations are less obvious. This
review will integrate what is known about the mechanisms of thyroid hormone action on the
heart2–5 with recent observations from both experimental and clinical studies of …
Thyroid hormone has many effects on the heart and vascular system.1 Many of the clinical manifestations of hyperthyroidism are due to the ability of thyroid hormone to alter cardiovascular hemodynamics.2 The hemodynamic effects of hypothyroidism are opposite to those of hyperthyroidism, although the clinical manifestations are less obvious. This review will integrate what is known about the mechanisms of thyroid hormone action on the heart25 with recent observations from both experimental and clinical studies of hyperthyroidism and hypothyroidism. We will also address the potential role of thyroid hormone treatment in patients with acute or chronic cardiac disease.
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The New England Journal Of Medicine