Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure …
Context Previous studies using autologous bone marrow mononuclear cells (BMCs) in
patients with ischemic cardiomyopathy have demonstrated safety and suggested efficacy.
Objective To determine if administration of BMCs through transendocardial injections
improves myocardial perfusion, reduces left ventricular end-systolic volume (LVESV), or
enhances maximal oxygen consumption in patients with coronary artery disease or LV
dysfunction, and limiting heart failure or angina. Design, Setting, and Patients A phase 2 …
patients with ischemic cardiomyopathy have demonstrated safety and suggested efficacy.
Objective To determine if administration of BMCs through transendocardial injections
improves myocardial perfusion, reduces left ventricular end-systolic volume (LVESV), or
enhances maximal oxygen consumption in patients with coronary artery disease or LV
dysfunction, and limiting heart failure or angina. Design, Setting, and Patients A phase 2 …