Wall stress in the normal and hypertrophied human left ventricle

WP Hood Jr, CE Rackley, EL Rolett - The American journal of cardiology, 1968 - Elsevier
WP Hood Jr, CE Rackley, EL Rolett
The American journal of cardiology, 1968Elsevier
By the use of angiocardiographic technics, normal ranges for end-diastolic and peak systolic
wall stresses have been defined in 6 subjects without left ventricular disease. In 41 other
patients with various forms of heart disease the anatomic and functional adaptations of the
left ventricle have been evaluated in terms of wall stress. Peak systolic stress appears to be
better than end-diastolic stress as an index of the appropriateness of the responses. The
data suggest that chronic valvular disease, representing a stimulus extrinsic to the …
Abstract
By the use of angiocardiographic technics, normal ranges for end-diastolic and peak systolic wall stresses have been defined in 6 subjects without left ventricular disease. In 41 other patients with various forms of heart disease the anatomic and functional adaptations of the left ventricle have been evaluated in terms of wall stress. Peak systolic stress appears to be better than end-diastolic stress as an index of the appropriateness of the responses. The data suggest that chronic valvular disease, representing a stimulus extrinsic to the myocardium, optimally results in a degree of hypertrophy appropriate to normalize peak systolic stress. In contrast, intrinsic muscle disease may result in a degree of hypertrophy inappropriate (either excessive or inadequate) in terms of peak stress. Normal peak stress does not preclude impaired cardiac performance, as in mitral stenosis, but elevated peak stress is characteristic of decompensated states.
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