Treatment of refractory status epilepticus with inhalational anesthetic agents isoflurane and desflurane

SM Mirsattari, MD Sharpe, GB Young - Archives of Neurology, 2004 - jamanetwork.com
Background Refractory status epilepticus (RSE) is defined as continued seizures after 2 or 3
antiepileptic drugs have failed. Several intravenous agents have been used for RSE;
however, problems occur with their toxicity and/or effectiveness. Objective To report our
experience with inhalational anesthesia (IA) in patients who were refractory to other
antiepileptic drugs. Design, Setting, and Participants Retrospective review during a 4-year
period of patients with RSE treated with isoflurane and/or desflurane. Main Outcome …