[HTML][HTML] Biological role of the CCAAT/enhancer-binding protein family of transcription factors
J Lekstrom-Himes, KG Xanthopoulos - Journal of Biological Chemistry, 1998 - ASBMB
CCAAT/enhancer-binding proteins (C/EBPs) comprise a family of transcription factors that
are critical for normal cellular differentiation and function in a variety of tissues. The
prototypic C/EBP is a modular protein, consisting of an activation domain, a dimerization
bZIP region, and a DNA-binding domain. All family members share the highly conserved
dimerization domain, required for DNA binding, by which they form homo-and heterodimers
with other family members. C/EBPs are least conserved in their activation domains and vary …
are critical for normal cellular differentiation and function in a variety of tissues. The
prototypic C/EBP is a modular protein, consisting of an activation domain, a dimerization
bZIP region, and a DNA-binding domain. All family members share the highly conserved
dimerization domain, required for DNA binding, by which they form homo-and heterodimers
with other family members. C/EBPs are least conserved in their activation domains and vary …