Reflecting on 25 years with MYC
N Meyer, LZ Penn - Nature Reviews Cancer, 2008 - nature.com
N Meyer, LZ Penn
Nature Reviews Cancer, 2008•nature.comJust over 25 years ago, MYC, the human homologue of a retroviral oncogene, was
identified. Since that time, MYC research has been intense and the advances impressive.
On reflection, it is astonishing how each incremental insight into MYC regulation and
function has also had an impact on numerous biological disciplines, including our
understanding of molecular oncogenesis in general. Here we chronicle the major advances
in our understanding of MYC biology, and peer into the future of MYC research.
identified. Since that time, MYC research has been intense and the advances impressive.
On reflection, it is astonishing how each incremental insight into MYC regulation and
function has also had an impact on numerous biological disciplines, including our
understanding of molecular oncogenesis in general. Here we chronicle the major advances
in our understanding of MYC biology, and peer into the future of MYC research.
Abstract
Just over 25 years ago, MYC, the human homologue of a retroviral oncogene, was identified. Since that time, MYC research has been intense and the advances impressive. On reflection, it is astonishing how each incremental insight into MYC regulation and function has also had an impact on numerous biological disciplines, including our understanding of molecular oncogenesis in general. Here we chronicle the major advances in our understanding of MYC biology, and peer into the future of MYC research.
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